Comparison of ligand migration and binding in heme proteins of the globin family
Nienhaus Karina), Ulrich Nienhaus G.†a),b),c)
       
(a) Essential features of the HbICO dimer. (b) Flash photolysis kinetics of CO rebinding (at 0.05-bar CO) in HbICO variants dissolved in buffer (closed symbols) and 75%/25% glycerol/buffer (open symbols), monitored at 436 nm and 20 °C. Black, wild-type HbI; green, I25W HbI; red: I114F HbI; purple, H69L HbI.