Comparison of ligand migration and binding in heme proteins of the globin family
Nienhaus Karina) , Ulrich Nienhaus G.†a), b), c) 
Comparison of ligand migration and binding in heme proteins of the globin family |
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Nienhaus Karin
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| (a) Essential features at the active site of wild-type MbCO. View onto the proximal (left) and the distal (right) sides of the structure. (b) Reaction free energy landscape describing ligand binding in Mb. (C. D) Flash photolysis kinetics of CO rebinding (at 1-bar CO) monitored at 436 nm and 20 °C. (c) Wild-type Mb (black symbols), I28F Mb (green), L104W Mb (blue), I107W Mb (red). (d) Wild-type Mb (black symbols), V68F Mb (green circles), V68Y Mb (green triangles), V68W Mb (green diamonds). |
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