Computational prediction of over-annotated protein-coding genes in the genome of <em> Agrobacterium tumefaciens</em> strain C58

Computational prediction of over-annotated protein-coding genes in the genome of Agrobacterium tumefaciens strain C58

Yu Jia-Feng†^a),^b), Sui Tian-Xiang^a),^d), Wang Hong-Mei^c), Wang Chun-Ling^c), Jing Li^c), Wang Ji-Hua^a),^c)

The relative G + C content at the three codon positions. As can be seen, the locating regions of the predicted non-coding genes are obviously different from those of the other genes. Careful observation indicates that the G + C content at the second and third codon positions of the protein-coding genes exhibit high usage bias. On the contrary, the values of relative G + C contents at the three codon positions of the predicted non-coding genes are about 1, respectively, which indicate that they are likely to be random sequences.