Self-assembled superparamagnetic nanoparticles as MRI contrast agents— A review
Su Hong-Ying†‡a) 
, Wu Chang-Qiang†b) , Li Dan-Yangc) , Ai Hua§b)
, Wu Chang-Qiang† 
Self-assembled superparamagnetic nanoparticles as MRI contrast agents— A review |
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Su Hong-Ying†‡
, Wu Chang-Qiang† |
| (a) Schematic diagram of Doxorubicin (Dox) and Fe3O4 nanoparticle-loaded PEG-PLA micelles, with cRGD peptides conjugated on the micelle surface. (b) TEM image of cRGD-DOXO-SPIO-loaded polymeric micelles (scale bars: 20 nm). (c) T 2 values of SLK cells treated with 16% cRGD-DOXO-SPIO micelles as a function of cell number. (d) and (e) Confocal laser scanning microscopic images of SLK cells treated with 0% and 16% cRGD-DOXO-SPIO micelles. Reprinted with permission from Ref. [ 10 ]. Copyright 2006, American Chemical Society. |
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