Self-assembled superparamagnetic nanoparticles as MRI contrast agents— A review
Su Hong-Ying†‡a), Wu Chang-Qiang†b), Li Dan-Yangc), Ai Hua§b)
       
(a) TEM image of Alkyl-PEI/SPIO nanocomposites (polymer/SPIO mass ratio = 0.6); (b) electron microscopic image of cells labeled with SPIO probes (arrows), scale bar = 100 nm; (c) T 2-weighted gradient echo image showing a prominent hypointense area of labeled injection in the right frame (19 d after transplantation); (d) ratios of signal intensities of the control and the labeled injection. Reprinted with permission from Ref. [ 13 ]. Copyright 2011, Elsevier Ltd.