Novel magnetic vortex nanorings/nanodiscs: Synthesis and theranostic applications
Liu Xiao-Lia),b), Yang Yonga), Wu Jian-Pengb), Zhang Yi-Fanb), Fan Hai-Mingb), Ding Jun†a)
       
(a) Comparison of SAR for FVIOs and Resovist in different fields. The frequency is at 400 kHz. (b) Simulated hysteresis loops along different directions. Inset shows the switching field ( H s) along different directions. (c) Schematics showing the effect of magnetic hyperthermia treatment on tumor cells in a mouse model. (d) Nude mice xenografted with breast cancer cells (MCF-7) before treatment (upper row, dotted circle) and 40 days after treatment (lower row) with untreated control, Resovist hyperthermia and FVIOs hyperthermia, respectively.[ 64 ] Reprinted with permission from Ref. [ 64 ], © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.