Colloidally deposited nanoparticle wires for biophysical detection |
(a) No significant resistance change in gold nanoparticle (14, 27, and 37 nm) wires with different concentrations of single-stranded DNA-binding protein (SSB). (b) The interaction sketch for single-strand DNA and SSB. (c), (d), and (e) Change in Δ R / R values for ssDNAs (600, 1200, and 3200 nucleotides (nt)) upon binding with SSB as a function of SSB concentrations. Gold nanoparticle wires with 37-nm gold nanoparticles were used for all experiments in panels (b), (c), and (d), and ssDNA concentrations were 0.001 nM, 0.01 nM, and 0.1 nM respectively.[ 54 ] |