中国物理B ›› 2018, Vol. 27 ›› Issue (9): 94302-094302.doi: 10.1088/1674-1056/27/9/094302

• ELECTROMAGNETISM, OPTICS, ACOUSTICS, HEAT TRANSFER, CLASSICAL MECHANICS, AND FLUID DYNAMICS • 上一篇    下一篇

Performance improvement of magneto-acousto-electrical tomography for biological tissues with sinusoid-Barker coded excitation

Zheng-Feng Yu(余正风), Yan Zhou(周), Yu-Zhi Li(李禹志), Qing-Yu Ma(马青玉), Ge-Pu Guo(郭各朴), Juan Tu(屠娟), Dong Zhang(章东)   

  1. 1 Jiangsu Provincial Engineering Laboratory of Audio Technology, School of Physics and Technology, Nanjing Normal University, Nanjing 210023, China;
    2 Institute of Acoustics, Nanjing University, Nanjing 210093, China
  • 收稿日期:2018-05-28 修回日期:2018-07-03 出版日期:2018-09-05 发布日期:2018-09-05
  • 通讯作者: Qing-Yu Ma E-mail:maqingyu@njnu.edu.cn
  • 基金资助:

    Project supported by the National Natural Science Foundation of China (Grant Nos. 11474166 and 11604156), the Natural Science Foundation of Jiangsu Province, China (Grant No. BK20161013), the Postdoctoral Science Foundation of China (Grant No. 2016M591874), the Postgraduate Research & Practice Innovation Program of Jiangsu Province, China (Grant No. KYCX17_1083), and the Priority Academic Program Development of Jiangsu Provincial Higher Education Institutions, China.

Performance improvement of magneto-acousto-electrical tomography for biological tissues with sinusoid-Barker coded excitation

Zheng-Feng Yu(余正风)1, Yan Zhou(周)1, Yu-Zhi Li(李禹志)1, Qing-Yu Ma(马青玉)1, Ge-Pu Guo(郭各朴)1, Juan Tu(屠娟)2, Dong Zhang(章东)2   

  1. 1 Jiangsu Provincial Engineering Laboratory of Audio Technology, School of Physics and Technology, Nanjing Normal University, Nanjing 210023, China;
    2 Institute of Acoustics, Nanjing University, Nanjing 210093, China
  • Received:2018-05-28 Revised:2018-07-03 Online:2018-09-05 Published:2018-09-05
  • Contact: Qing-Yu Ma E-mail:maqingyu@njnu.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Grant Nos. 11474166 and 11604156), the Natural Science Foundation of Jiangsu Province, China (Grant No. BK20161013), the Postdoctoral Science Foundation of China (Grant No. 2016M591874), the Postgraduate Research & Practice Innovation Program of Jiangsu Province, China (Grant No. KYCX17_1083), and the Priority Academic Program Development of Jiangsu Provincial Higher Education Institutions, China.

摘要:

By combining magnetics, acoustics and electrics, the magneto-acoustic-electrical tomography (MAET) proves to possess the capability of differentiating electrical impedance variation and thus improving the spatial resolution. However, the signal-to-noise ratio (SNR) of the collected MAET signal is still unsatisfactory for biological tissues with low-level electrical conductivity. In this study, the formula of MAET measurement with sinusoid-Barker coded excitation is derived and simplified for a planar piston transducer. Numerical simulations are conducted for a four-layered gel phantom with the 13-bit sinusoid-Barker coded excitation, and the performances of wave packet recovery with side-lobe suppression are improved by using the mismatched compression filter, which is also demonstrated by experimentally measuring a three-layered gel phantom. It is demonstrated that comparing with the single-cycle sinusoidal excitation, the amplitude of the driving signal can be reduced greatly with an SNR enhancement of 10 dB using the 13-bit sinusoid-Barker coded excitation. The amplitude and polarity of the wave packet filtered from the collected MAET signal can be used to achieve the conductivity derivative at the tissue boundary. In this study, we apply the sinusoid-Barker coded modulation method and the mismatched suppression scheme to MAET measurement to ensure the safety for biological tissues with improved SNR and spatial resolution, and suggest the potential applications in biomedical imaging.

关键词: magneto-acousto-electrical tomography, sinusoid-Barker coded excitation, mismatched compression filter, side lobe suppression

Abstract:

By combining magnetics, acoustics and electrics, the magneto-acoustic-electrical tomography (MAET) proves to possess the capability of differentiating electrical impedance variation and thus improving the spatial resolution. However, the signal-to-noise ratio (SNR) of the collected MAET signal is still unsatisfactory for biological tissues with low-level electrical conductivity. In this study, the formula of MAET measurement with sinusoid-Barker coded excitation is derived and simplified for a planar piston transducer. Numerical simulations are conducted for a four-layered gel phantom with the 13-bit sinusoid-Barker coded excitation, and the performances of wave packet recovery with side-lobe suppression are improved by using the mismatched compression filter, which is also demonstrated by experimentally measuring a three-layered gel phantom. It is demonstrated that comparing with the single-cycle sinusoidal excitation, the amplitude of the driving signal can be reduced greatly with an SNR enhancement of 10 dB using the 13-bit sinusoid-Barker coded excitation. The amplitude and polarity of the wave packet filtered from the collected MAET signal can be used to achieve the conductivity derivative at the tissue boundary. In this study, we apply the sinusoid-Barker coded modulation method and the mismatched suppression scheme to MAET measurement to ensure the safety for biological tissues with improved SNR and spatial resolution, and suggest the potential applications in biomedical imaging.

Key words: magneto-acousto-electrical tomography, sinusoid-Barker coded excitation, mismatched compression filter, side lobe suppression

中图分类号:  (Acoustical measurement methods in biological systems and media)

  • 43.80.Ev
72.55.+s (Magnetoacoustic effects)