中国物理B ›› 2015, Vol. 24 ›› Issue (1): 14704-014704.doi: 10.1088/1674-1056/24/1/014704

所属专题: TOPICAL REVIEW — Magnetism, magnetic materials, and interdisciplinary research

• SPECIAL TOPIC --- Non-equilibrium phenomena in soft matters • 上一篇    下一篇

Surface modification of magnetic nanoparticles in biomedicine

储鑫, 余靓, 侯仰龙   

  1. Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China
  • 收稿日期:2014-11-04 修回日期:2014-12-09 出版日期:2015-01-05 发布日期:2015-01-05
  • 基金资助:

    Project supported by the National Natural Science Foundation of China (Grant Nos. 51125001 and 51172005), the Natural Science Foundation of Beijing, China (Grant No. 2122022), the Science Fund for Creative Research Groups of the National Natural Science Foundation of China (Grant No. 81421004), and the Doctoral Program of the Education Ministry of China (Grant No. 20120001110078).

Surface modification of magnetic nanoparticles in biomedicine

Chu Xin (储鑫), Yu Jing (余靓), Hou Yang-Long (侯仰龙)   

  1. Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China
  • Received:2014-11-04 Revised:2014-12-09 Online:2015-01-05 Published:2015-01-05
  • Contact: Hou Yang-Long E-mail:hou@pku.edu.cn
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Grant Nos. 51125001 and 51172005), the Natural Science Foundation of Beijing, China (Grant No. 2122022), the Science Fund for Creative Research Groups of the National Natural Science Foundation of China (Grant No. 81421004), and the Doctoral Program of the Education Ministry of China (Grant No. 20120001110078).

摘要:

Progress in surface modification of magnetic nanoparticles (MNPs) is summarized with regard to organic molecules, macromolecules and inorganic materials. Many researchers are now devoted to synthesizing new types of multi-functional MNPs, which show great application potential in both diagnosis and treatment of disease. By employing an ever-greater variety of surface modification techniques, MNPs can satisfy more and more of the demands of medical practice in areas like magnetic resonance imaging (MRI), fluorescent marking, cell targeting, and drug delivery.

关键词: magnetic nanoparticles, surface modification, functionalization, magnetic resonance imaging

Abstract:

Progress in surface modification of magnetic nanoparticles (MNPs) is summarized with regard to organic molecules, macromolecules and inorganic materials. Many researchers are now devoted to synthesizing new types of multi-functional MNPs, which show great application potential in both diagnosis and treatment of disease. By employing an ever-greater variety of surface modification techniques, MNPs can satisfy more and more of the demands of medical practice in areas like magnetic resonance imaging (MRI), fluorescent marking, cell targeting, and drug delivery.

Key words: magnetic nanoparticles, surface modification, functionalization, magnetic resonance imaging

中图分类号:  (Transport processes and drug delivery)

  • 47.63.mh
87.19.lf (MRI: anatomic, functional, spectral, diffusion) 87.57.-s (Medical imaging) 87.61.-c (Magnetic resonance imaging)