%A Xiaowei Liu(刘小威), Chao Meng(孟超), Xuechu Xu(徐雪初), Mingwei Tang(汤明炜), Chenlei Pang(庞陈雷), Qing Yang(杨青) %T Applications of nanostructures in wide-field, label-free super resolution microscopy %0 Journal Article %D 2018 %J Chin. Phys. B %R 10.1088/1674-1056/27/11/118704 %P 118704-118704 %V 27 %N 11 %U {https://cpb.iphy.ac.cn/CN/abstract/article_121174.shtml} %8 2018-11-05 %X

Super resolution imaging capable of resolving details beyond the diffraction limit is highly desired in many scientific and application fields, including bio-medicine, nanomaterial science, and opto-electronic integration. Up to now, many different methods have been proposed, among which wide-field, label-free super resolution microscopy is indispensable due to its good applicability to diverse sample types, large field of view (FOV), and high imaging speed. In recent years, nanostructures have made a crucial contribution to the wide-field, label-free subdiffraction microscopy, with various working mechanisms and configuration designs. This review summarizes the recent applications of the nanostructures in the wide-field, label-free super resolution microscopy, with the emphasis on the designs of hyperlens with hyperbolic dispersion, microsphere with “nano-jets”, and nanowire ring illumination microscopy based on spatial frequency shift effect. The bottlenecks of the current techniques and possible solutions are also discussed.