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Chin. Phys. B, 2014, Vol. 23(1): 010202    DOI: 10.1088/1674-1056/23/1/010202
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Control of epileptiform spikes based on nonlinear unscented Kalman filter

Liu Xian (刘仙), Gao Qing (高庆), Li Xiao-Li (李小俚)
Key Lab of Industrial Computer Control Engineering of Hebei Province, Institute of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China
Abstract  A new control strategy based on nonlinear unscented Kalman filter (UKF) is proposed for a neural mass model that serves as a model for simulating real epileptiform stereo-electroencephalographic (SEEG) signals. The UKF is used as an observer to estimate the state from the noisy measurement because it has been proved to be effective for state estimation of nonlinear systems. A UKF controller is constructed via the estimated state and is illustrated to be effective for epileptiform spikes suppression of aforementioned model by numerical simulations.
Keywords:  unscented Kalman filter (UKF) control      epileptiform spike      closed-loop control      neural mass model  
Received:  04 March 2013      Revised:  07 June 2013      Accepted manuscript online: 
PACS:  02.30.Yy (Control theory)  
  87.19.le (EEG and MEG)  
Fund: Project supported by the National Natural Science Foundation of China (Grant Nos. 61004050 and 60125019) and the Natural Science Foundation of Scientific Research of Hebei Education Department, China (Grant No. 2009482).
Corresponding Authors:  Liu Xian     E-mail:  liuxian@ysu.edu.cn

Cite this article: 

Liu Xian (刘仙), Gao Qing (高庆), Li Xiao-Li (李小俚) Control of epileptiform spikes based on nonlinear unscented Kalman filter 2014 Chin. Phys. B 23 010202

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