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Chin. Phys. B, 2015, Vol. 24(1): 014704    DOI: 10.1088/1674-1056/24/1/014704
Special Issue: TOPICAL REVIEW — Magnetism, magnetic materials, and interdisciplinary research
TOPICAL REVIEW—Magnetism, magnetic materials, and interdisciplinary research Prev   Next  

Surface modification of magnetic nanoparticles in biomedicine

Chu Xin, Yu Jing, Hou Yang-Long
Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China

Progress in surface modification of magnetic nanoparticles (MNPs) is summarized with regard to organic molecules, macromolecules and inorganic materials. Many researchers are now devoted to synthesizing new types of multi-functional MNPs, which show great application potential in both diagnosis and treatment of disease. By employing an ever-greater variety of surface modification techniques, MNPs can satisfy more and more of the demands of medical practice in areas like magnetic resonance imaging (MRI), fluorescent marking, cell targeting, and drug delivery.

Keywords:  magnetic nanoparticles      surface modification      functionalization      magnetic resonance imaging  
Received:  04 November 2014      Revised:  09 December 2014      Accepted manuscript online: 
PACS: (Transport processes and drug delivery)  
  87.19.lf (MRI: anatomic, functional, spectral, diffusion)  
  87.57.-s (Medical imaging)  
  87.61.-c (Magnetic resonance imaging)  

Project supported by the National Natural Science Foundation of China (Grant Nos. 51125001 and 51172005), the Natural Science Foundation of Beijing, China (Grant No. 2122022), the Science Fund for Creative Research Groups of the National Natural Science Foundation of China (Grant No. 81421004), and the Doctoral Program of the Education Ministry of China (Grant No. 20120001110078).

Corresponding Authors:  Hou Yang-Long     E-mail:

Cite this article: 

Chu Xin, Yu Jing, Hou Yang-Long Surface modification of magnetic nanoparticles in biomedicine 2015 Chin. Phys. B 24 014704

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