中国物理B ›› 2009, Vol. 18 ›› Issue (2): 658-663.doi: 10.1088/1674-1056/18/2/044

• CONDENSED MATTER: STRUCTURAL, MECHANICAL, AND THERMAL PROPERTIES • 上一篇    下一篇

Pair interaction of bilayer-coated nanoscopic particles

张启义   

  1. Department of Mathematics and Physics, Chongqing University of Science and Technology, Chongqing 401331, China
  • 收稿日期:2008-07-11 修回日期:2008-08-09 出版日期:2009-02-20 发布日期:2009-02-20
  • 基金资助:
    Project supported by the National Natural Science Foundation of China (Grant No 20804060).

Pair interaction of bilayer-coated nanoscopic particles

Zhang Qi-Yi(张启义)†   

  1. Department of Mathematics and Physics, Chongqing University of Science and Technology, Chongqing 401331, China
  • Received:2008-07-11 Revised:2008-08-09 Online:2009-02-20 Published:2009-02-20
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Grant No 20804060).

PDF (PC)

554

赞

摘要： The pair interaction between bilayer membrane-coated nanosized particles has been explored by using the self-consistent field (SCF) theory. The bilayer membranes are composed of amphiphilic polymers. For different system parameters, the pair-interaction free energies are obtained. Particular emphasis is placed on the analysis of a sequence of structural transformations of bilayers on spherical particles, which occur during their approaching processes. For different head fractions of amphiphiles, the asymmetrical morphologies between bilayers on two particles and the inverted micellar intermediates have been found in the membrane fusion pathway. These results can benefit the fabrication of vesicles as encapsulation vectors for drug and gene delivery.

Abstract: The pair interaction between bilayer membrane-coated nanosized particles has been explored by using the self-consistent field (SCF) theory. The bilayer membranes are composed of amphiphilic polymers. For different system parameters, the pair-interaction free energies are obtained. Particular emphasis is placed on the analysis of a sequence of structural transformations of bilayers on spherical particles, which occur during their approaching processes. For different head fractions of amphiphiles, the asymmetrical morphologies between bilayers on two particles and the inverted micellar intermediates have been found in the membrane fusion pathway. These results can benefit the fabrication of vesicles as encapsulation vectors for drug and gene delivery.

Key words: bilayer membrane, inverted micellar intermediates, nanoparticle, self-consistent field theory

中图分类号:  (Membranes, bilayers, and vesicles)

  • 87.16.D-
87.15.K- (Molecular interactions; membrane-protein interactions) 87.14.Cc (Lipids) 87.85.Qr (Nanotechnologies-design) 05.70.Ce (Thermodynamic functions and equations of state)