中国物理B ›› 2014, Vol. 23 ›› Issue (4): 48702-048702.doi: 10.1088/1674-1056/23/4/048702

• INTERDISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY • 上一篇    下一篇

Cardiac electrical activity imaging of patients with CRBBB or CLBBB in magnetocardiography

朱俊杰a, 蒋式勤a, 王伟远a, 赵晨a, 吴燕华a, 罗明b, 权薇薇c   

  1. a Department of Control Science and Engineering, School of Electronics and Information Engineering, Tongji University, Shanghai 201804, China;
    b Department of Cardiology of Tongji Hospital Affiliated to Tongji University Medical School, Shanghai 200065, China;
    c Department of Cardiology of Ruijin Hospital Affiliated to Jiaotong University Medical School, Shanghai 200025, China
  • 收稿日期:2013-09-07 修回日期:2013-11-05 出版日期:2014-04-15 发布日期:2014-04-15
  • 基金资助:
    Project supported in part by the National Natural Science Foundation of China (Grant No. 60771030), the National High-Technology Research and Development Program of China (Grant No. 2008AA02Z308), the Shanghai Science and Technology Development Foundation (Grant No. 08JC1421800), the Shanghai Leading Academic DisciplineProject (Grant No. B004), the OpenProject of State Key Laboratory of Function Materials for Information (Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences), and the Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention of Shanghai (Grant No. 13DZ2272200-2).

Cardiac electrical activity imaging of patients with CRBBB or CLBBB in magnetocardiography

Zhu Jun-Jie (朱俊杰)a, Jiang Shi-Qin (蒋式勤)a, Wang Wei-Yuan (王伟远)a, Zhao Chen (赵晨)a, Wu Yan-Hua (吴燕华)a, Luo Ming (罗明)b, Quan Wei-Wei (权薇薇)c   

  1. a Department of Control Science and Engineering, School of Electronics and Information Engineering, Tongji University, Shanghai 201804, China;
    b Department of Cardiology of Tongji Hospital Affiliated to Tongji University Medical School, Shanghai 200065, China;
    c Department of Cardiology of Ruijin Hospital Affiliated to Jiaotong University Medical School, Shanghai 200025, China
  • Received:2013-09-07 Revised:2013-11-05 Online:2014-04-15 Published:2014-04-15
  • Contact: Jiang Shi-Qin E-mail:sqjiang@tongji.edu.cn
  • About author:87.85.-d; 87.85.Pq; 87.85.Tu; 87.85.Ng
  • Supported by:
    Project supported in part by the National Natural Science Foundation of China (Grant No. 60771030), the National High-Technology Research and Development Program of China (Grant No. 2008AA02Z308), the Shanghai Science and Technology Development Foundation (Grant No. 08JC1421800), the Shanghai Leading Academic DisciplineProject (Grant No. B004), the OpenProject of State Key Laboratory of Function Materials for Information (Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences), and the Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention of Shanghai (Grant No. 13DZ2272200-2).

摘要: A new method for the imaging of cardiac electrical activity in patients with complete right bundle branch block (CRBBB) or complete left bundle branch block (CLBBB) is investigated using magnetocardiographic recordings of the surface of the body. This is based on the assumption that an equivalent single-current dipole moves along the unblocked bundle branch, whose position in the measurement plane is expressed in terms of the maximum and minimum, as well as the maximum gradient value of the measured magnetic field. The trajectory of the moving dipole on the measurement plane is indicative of the excitation conduction of the CRBBB or CLBBB subject during ventricular depolarization and repolarization, which is deduced by comparing each change between the dipole moment and the maximum current density in a corresponding pseudo-current density map. In summary, this method can distinguish CRBBB from CLBBB subjects by means of the dipole depth and two dipole moment components. The possibility of visualizing the excitation conduction in a CRBBB or CLBBB subject during ventricular depolarization and repolarization is then discussed.

关键词: biomagnetism, inverse problem, magnetocardiography (MCG), current source reconstruction (CSR), CRBBB or CLBBB

Abstract: A new method for the imaging of cardiac electrical activity in patients with complete right bundle branch block (CRBBB) or complete left bundle branch block (CLBBB) is investigated using magnetocardiographic recordings of the surface of the body. This is based on the assumption that an equivalent single-current dipole moves along the unblocked bundle branch, whose position in the measurement plane is expressed in terms of the maximum and minimum, as well as the maximum gradient value of the measured magnetic field. The trajectory of the moving dipole on the measurement plane is indicative of the excitation conduction of the CRBBB or CLBBB subject during ventricular depolarization and repolarization, which is deduced by comparing each change between the dipole moment and the maximum current density in a corresponding pseudo-current density map. In summary, this method can distinguish CRBBB from CLBBB subjects by means of the dipole depth and two dipole moment components. The possibility of visualizing the excitation conduction in a CRBBB or CLBBB subject during ventricular depolarization and repolarization is then discussed.

Key words: biomagnetism, inverse problem, magnetocardiography (MCG), current source reconstruction (CSR), CRBBB or CLBBB

中图分类号:  (Biomedical engineering)

  • 87.85.-d
87.85.Pq (Biomedical imaging) 87.85.Tu (Modeling biomedical systems) 87.85.Ng (Biological signal processing)